Doctor checks blood pressure of a patient wearing a headscarf indoors, focused on healthcare.

Vulvar Cancer

Vulvar cancer develops in the vulva, the external female genital area (including the labia, clitoris, and vaginal opening). It is a rare cancer but often treatable when detected early. Most cases occur in women over 60, though it can affect younger women.

2. Causes & Risk Factors

  • HPV Infection: Some cases link to high-risk human papillomavirus (HPV), especially in younger women.
  • Chronic Skin Conditions: Lichen sclerosis (a condition causing itchy, white patches) or vulvar intraepithelial neoplasia (VIN, pre-cancerous cell changes).
  • Age: Risk increases with age.
  • Smoking: Weakens immunity and increases cancer risk.
  • Weakened Immune System: Due to conditions like HIV or organ transplant medications.

3. Symptoms

  • Itching, burning, or pain in the vulvar area.
  • Lumps, sores, or thickened skin on the vulva.
  • Bleeding not related to menstruation.
  • Colour changes (red, white, or dark patches).
  • Pain during urination or sex.

4. Prevention

  • HPV Vaccine: Protects against high-risk HPV strains (recommended for ages 9–45).
  • Avoid Smoking: Reduces cancer risk.
  • Manage Skin Conditions: Treat lichen sclerosis or VIN promptly.
  • Safe Sex: Use condoms to lower HPV exposure.
  • Regular Self-Exams: Check the vulva for changes and report them.

5. Screening

  • Routine Screening: Unlike cervical cancer, there’s no standard screening test.
  • High-Risk Individuals: Regular pelvic exams and biopsies of suspicious areas.
  • Symptom Awareness: Persistent vulvar symptoms warrant immediate evaluation.

6. Diagnosis & Treatment

  • Diagnosis:
    • Pelvic Exam: Visual and physical check of the vulva.
    • Biopsy: Removal of a tissue sample for testing (definitive diagnosis).
    • Imaging: CT/MRI scans to check for spread.
  • Treatment Options:
    • Surgery: Removal of cancerous tissue (e.g., wide local excision, vulvectomy).
    • Radiation: For advanced cases or recurrence.
    • Chemotherapy/Targeted Therapy: Used in combination with other treatments.

Frequently Asked Questions

  • Is vulvar cancer linked to HPV? 

Yes, in about 40–60% of cases.

  • Can a smear (Pap) test detect it? 

No—Cervical smear tests for cervical cancer only.

  • Is it hereditary? 

Rarely, but family history of vulvar or other cancers may increase risk.

  • What’s the survival rate? 

Early-stage diagnosis has an 80–90% 5-year survival rate.

  • Can it recur? 

Yes, follow-up care is critical.

eGynaecologist Advice:

  • You must consult a gynaecologist if you have persistent vulvar itching, lumps, or skin changes
  • You should have regular check ups with your doctor if you have lichen sclerosis or VIN
  • Symptoms of vulvar cancer are often mistaken for infections or skin conditions. You must consult a gynaecologist if you suffer from persistent changes to vulva.
  • Regular follow up checks after treatment with your gynaecologist are important to monitor your health and prevent complications of recurrence of cancer